Absolutely not. BPA was commonly used in plastics up to the last decade, when concerns arose about its affect on human endocrine systems. Invisalign products and Vivera Retainers contain no Bisphenol-A or phthalate plasticizers. All of our products are made with medical-grade, high molecular weight, polyurethane resins. Tests show that they are biocompatible and pass all thresholds for human wear in the mouth. Feel free to consult with Carmichael’s Dr. Alizadeh or your medical health professional if you have any concerns.